Obesity Research & Clinical Practice
Volume 3, Issue 4 , Pages 203-207 , November 2009

Proinflammatory and phagocytic functions of alveolar macrophages in obesity

  • Ali El Solh

      Affiliations

    • Veterans Affairs Western New York Healthcare System, Buffalo, NY, United States
    • Western New York Respiratory Research Center, Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, United States
    • Corresponding Author InformationCorresponding author at: Medical Research, Bldg. 20 (151), VISN02, Veterans Affairs Western New York Healthcare System, 3495 Bailey Avenue, Buffalo, NY 14215-1199, United States. Tel.: +1 716 862 7366; fax: +1 425 675 4502.
  • ,
  • Jahan Porhomayon

      Affiliations

    • Veterans Affairs Western New York Healthcare System, Buffalo, NY, United States
    • Department of Anesthesia, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, United States
  • ,
  • Krsitie Szarpa

      Affiliations

    • Western New York Respiratory Research Center, Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, United States

Received 23 March 2009 ,Revised 30 April 2009 ,Accepted 3 May 2009.

  • Image Result

    Alveolar macrophages production of TNF-α at baseline and after LPS stimulation in nonobese (n=6), obese (n=6), and morbidly obese subjects (n=6).

    Alveolar macrophages production of TNF-α at baseline and after LPS stimulation in nonobese (n=6), obese (n=6), and morbidly obese subjects (n=6).

  • Image Result

    Comparison of the percentage of alveolar macrophages ingesting both opsonized (white bars) and unopsonized particles (gray bars) between nonobese (n=6), obese (n=6), and morbidly obese subjects (n=6).

    Comparison of the percentage of alveolar macrophages ingesting both opsonized (white bars) and unopsonized particles (gray bars) between nonobese (n=6), obese (n=6), and morbidly obese subjects (n=6).

  • Image Result
    Comparison of the percentage of Listeria monocytogenes killed by alveolar macrophages at 30, 60, and 90min incubation between nonobese (n=6), obese (n=6), and morbidly obese subjects (n=6).

    Comparison of the percentage of Listeria monocytogenes killed by alveolar macrophages at 30, 60, and 90min incubation between nonobese (n=6), obese (n=6), and morbidly obese subjects (n=6).

PII: S1871-403X(09)00039-8

doi: 10.1016/j.orcp.2009.05.001

Obesity Research & Clinical Practice
Volume 3, Issue 4 , Pages 203-207 , November 2009